Novel RGD containing, temozolomide-loading nanostructured lipid carriers for glioblastoma multiforme chemotherapy
نویسندگان
چکیده
منابع مشابه
Improvement of fluvastatin bioavailability by loading on nanostructured lipid carriers
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INTRODUCTION The use of adjuvant temozolomide (TMZ) in patients managed with surgery and adjuvant radiation therapy (RT) for glioblastoma multiforme (GBM) has been demonstrated to improve median and 2-year survival in a recent large international multicentre study. To confirm this result in routine clinical practice, an audit of the management and outcome of patients with GBM at The Cancer Inst...
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Local recurrence represents a significant challenge in the management of patients with glioblastoma multiforme. Salvage treatment options are limited by lack of clinical efficacy. Recent studies have demonstrated a significant response rate and acceptable toxicity with the use of fractionated stereotactic radiosurgery in this patient population. Our primary objective was to determine the effica...
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ژورنال
عنوان ژورنال: Drug Delivery
سال: 2015
ISSN: 1071-7544,1521-0464
DOI: 10.3109/10717544.2015.1064186